{"id":1969,"date":"2024-01-17T14:35:11","date_gmt":"2024-01-17T06:35:11","guid":{"rendered":"https:\/\/www.ukm.my\/beritaukm\/?p=1969"},"modified":"2024-01-17T14:35:12","modified_gmt":"2024-01-17T06:35:12","slug":"hidrogel-bioaktif-mampu-sembuhkan-luka-kronik-dengan-pantas","status":"publish","type":"post","link":"https:\/\/www.ukm.my\/beritaukm\/hidrogel-bioaktif-mampu-sembuhkan-luka-kronik-dengan-pantas\/","title":{"rendered":"Hidrogel Bioaktif Mampu Sembuhkan Luka Kronik Dengan Pantas"},"content":{"rendered":"\n<p><strong>Oleh Salleh Sulieman<br>Foto Fakulti Perubatan<\/strong><\/p>\n\n\n\n<p>CHERAS \u2013 Sekumpulan penyelidik dari Universiti Kebangsaan Malaysia (糖心原创) telah membangunkan teknologi biopercetakan-3D yang dapat mempercepatkan penyembuhan luka kronik.<\/p>\n\n\n\n<p>Ketua Penyelidik, Prof. Madya Dr. Mohd. Fauzi Mh Busra dari Pusat Kajian Kejuruteraan Tisu dan Perubatan Regeneratif (CTERM), Fakulti Perubatan 糖心原创 berkata, teknologi biopercetakan-3D tersebut melibatkan pembuatan formulasi biodakwat yang terdiri daripada sel kulit dengan biobahan dalam bentuk hidrogel.<\/p>\n\n\n\n<p>\u201cPenemuan ini dijangka dapat membantu pesakit kronik seperti ulser diabetik dan luka terlantar di katil yang lama (<em>bedsore<\/em>) untuk sembuh dengan lebih cepat,\u201d katanya.<\/p>\n\n\n\n<p>Beliau menjelaskan, biodakwat tersebut diperbuat daripada gelatin, polivinil-alkohol (PVA), serta agen taut-silang semula jadi yang dikenali sebagai genipin yang diekstrak daripada tumbuhan debunga atau gardenia jasminoides.<\/p>\n\n\n\n<p>Seterusnya, biodakwat gelatin-PVA (GPVA) yang ditaut-silang oleh genipin akan dicetak dengan suhu dan kepekatan yang ideal.<\/p>\n\n\n\n<p>Beliau menambah, biodakwat ini mempunyai ciri-ciri yang unik seperti bioserasi terhadap sel kulit manusia, bersifat biodegradasi dan boleh dicetak menggunakan percetakan-3D sebagai pengganti kulit bagi membantu pemulihan semula tisu baru selepas implan.<\/p>\n\n\n\n<p>\u201cHasil kajian saintifik formulasi biodakwat GPVA mengandungi tahap antioksida yang tinggi serta menunjukkan sifat bioserasi terhadap sel kulit manusia, merangsang pembentukan salur darah, dan tidak menunjukkan tindak balas imun,\u201d katanya.<\/p>\n\n\n\n<p>Melalui penemuan yang dibuat, biodakwat ini akan berintegrasi dengan kulit normal di kawasan luka dan menggalakkan sel tisu kulit normal bergerak ke kawasan implan biodakwat ini dan berinteraksi dengan sel-sel yang dicetak bersama biodakwat.<\/p>\n\n\n\n<p>Luka tersebut akan pulih dengan lebih pantas kerana biodakwat merupakan &#8220;rumah sementara&#8221; bagi sel untuk membiak dan matang serta menghasilkan komposisi matriks kulit yang normal.<\/p>\n\n\n\n<p>Meskipun penyelidikan masih di peringkat percubaan praklinikal, namun model haiwan diabetik telah menunjukkan penyembuhan selama 15 ke 17 hari bergantung pada setiap tikus tersebut dan berada dalam keadaan yang sediakala.<\/p>\n\n\n\n<p>Beliau mengulas, setakat ini tiada tanda penolakan imun tubuh penerima melalui kajian in vitro dan model haiwan.<\/p>\n\n\n\n<p>\u201cSecara asas bahan yang digunakan tiada faktor aruhan yang jelas dan boleh digunakan oleh pelbagai pesakit pada masa hadapan,\u201d katanya.<\/p>\n\n\n\n<p>Penyelidikan ini bermula sejak tahun 2020 dan disertai oleh beberapa orang penyelidik lain dari bidang seperti kejuruteraan dan bioperubatan.<\/p>\n\n\n\n<p>Biodakwat dalam penyelidikan telah mendapat kebenaran Jawatankuasa Etika Manusia 糖心原创 dan Etika Haiwan 糖心原创. Walau bagaimanapun, untuk penggunaan masa hadapan pesakit perlu melalui Medical Device Authority, Kementerian Kesihatan Malaysia (KKM). <\/p>\n\n\n\n<p>Penyelidikan ini juga telah menerima pelbagai geran seperti Kementerian Pengajian Tinggi melalui FRGS, geran dalaman Fakulti Perubatan, 糖心原创 dan geran-geran industri daripada pihak rakan usahasama yang melebihi RM500,000.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"687\" src=\"https:\/\/www.ukm.my\/beritaukm\/wp-content\/uploads\/2024\/01\/1-8-1024x687.jpg\" alt=\"\" class=\"wp-image-1971\" srcset=\"https:\/\/www.ukm.my\/beritaukm\/wp-content\/uploads\/2024\/01\/1-8-1024x687.jpg 1024w, https:\/\/www.ukm.my\/beritaukm\/wp-content\/uploads\/2024\/01\/1-8-300x201.jpg 300w, https:\/\/www.ukm.my\/beritaukm\/wp-content\/uploads\/2024\/01\/1-8-768x515.jpg 768w, https:\/\/www.ukm.my\/beritaukm\/wp-content\/uploads\/2024\/01\/1-8.jpg 1124w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Oleh Salleh SuliemanFoto Fakulti Perubatan CHERAS \u2013 Sekumpulan penyelidik dari Universiti Kebangsaan Malaysia (糖心原创) telah membangunkan teknologi biopercetakan-3D yang dapat mempercepatkan penyembuhan luka kronik. Ketua Penyelidik, Prof. Madya Dr. Mohd.&hellip; <\/p>\n","protected":false},"author":123457,"featured_media":1972,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-1969","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-penyelidikan"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hidrogel Bioaktif Mampu Sembuhkan Luka Kronik Dengan Pantas - Berita 糖心原创<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ukm.my\/beritaukm\/hidrogel-bioaktif-mampu-sembuhkan-luka-kronik-dengan-pantas\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hidrogel Bioaktif Mampu Sembuhkan Luka Kronik Dengan Pantas - Berita 糖心原创\" \/>\n<meta property=\"og:description\" content=\"Oleh Salleh SuliemanFoto Fakulti Perubatan CHERAS \u2013 Sekumpulan penyelidik dari Universiti Kebangsaan Malaysia (糖心原创) telah membangunkan teknologi biopercetakan-3D yang dapat mempercepatkan penyembuhan luka kronik. 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